Cell Therapy Development Services

Cell Therapy Development Services

Cell therapy has been booming in the field of therapeutics of various diseases. It has been significantly expected the application that stem cells, immune cells, or other specialized cells are manipulated and reintroduced into patients with autoimmune diseases to defend against the inflammatory response. Our company provides cutting-edge research services to help you develop highly potent therapeutic cells and accelerate the cell therapy development in Autoimmune Diseases & Inflammation.

Cell Therapy in Autoimmune Diseases & Inflammation

Cell Therapy is currently in its infancy in the realm of treating Autoimmune Diseases & Inflammation. In the long process of developing therapeutic antibodies for autoimmune diseases, the pathogenesis in many aspects has been solved. However, therapeutic antibodies still have shortcomings in efficacy and specificity. The emergence of cell therapy in recent years provides a more powerful tool for the therapeutics of autoimmune diseases, which can provide tailored therapeutics options, reduce the frequency, and even take into account both regulation of the immune system and repairs of damaged tissues.

A schematic representation of the mechanisms of action of tolerogenic cellsFig.1 A schematic representation of the mechanisms of action of tolerogenic cells (Mosanya C.H., et al., 2019)

Depending on the specific purpose of different therapies, a variety of cells can be used as a medium for cell therapy. The ability of immune cells to maintain the balance of the immune system is core to their role in regulating inflammation and expediting the repair of damaged areas within the immune system. The engineered T lymphocytes, natural killer cells (NKCs), dendritic cells (DCs), B cells and macrophage playing various roles in the immune system can enhance the attack power of the immune system, produce specific antibodies, or suppress inflammation. Additionally, the stem cells, including mesenchymal stem cell (MSCs), hematopoietic stem cells (HSCs) and induced pluripotent cells (iPSCs), have played a significant role in immune regulation, tissue repair, and immune tolerance, which cannot be overlooked.

Cell Therapy ID Process Indication Location
Treg Cells NCT02932826 Phase I/II Type I Diabetes China
Treg Cells NCT04691232 Phase I Ulcerative Colitis Germany
CAR-T Cells NCT05459870 Phase I/II B Cell Related Autoimmune Diseases China
CAR-T Cells NCT05474885 Phase I Systemic Lupus Erythematosus China
Stem Cells NCT00716066 Phase II Multiple Sclerosis United States
Stem Cells NCT02997878 Phase I/II Autoimmune Hepatitis United Kingdom
Dendritic Cells NCT04530318 Phase II Multiple Sclerosis Spain
Dendritic Cells NCT05251870 Phase I/II Rheumatoid Arthritis Netherlands
B cells NCT03747159 Phase III Systemic Lupus Erythematosus Netherlands

At present, plenty of pharmaceutical companies or research teams around the world are conducting clinical trials or being approved for cell therapies for autoimmune diseases. It not only represents the latest progress in medical science, but also a key step towards more individualized and precise treatment in Autoimmune Diseases & Inflammation.

Our Services

Although facing numerous challenges, the therapeutic development of immune cells, stem cells, and other cells has shown tremendous potential in the treatment of Autoimmune Diseases & Inflammation. With comprehensive development capabilities, we provide cell therapy development utilizing distinct cell types, including but not limited to:

Workflow of Cell Therapy Development

Our Services

Our Advantages

  • Rigorous experimental operation and analysis
  • Customized programs designed by experts in cell biology
  • Rapid trial turnaround time
  • High-level professional technical team

Our Advantages

Staffed by the researchers from cell engineering biology and immunology with extensive experience in the development of successful cell therapies, our company is committed to providing you with professional services for the cell therapy development for Autoimmune Diseases & Inflammation. Please contact us for more detailed information and our team will get back to you promptly.

Reference

  1. Mosanya, Chijioke H, and John D Isaacs. "Tolerising cellular therapies: what is their promise for autoimmune disease?" Annals of the rheumatic diseases 78,3 (2019): 297-310.
For research use only. Not intended for any clinical use.